With their romance exposed, Sydney and Adrian face the wrath of the Alchemists and the Moroi alike as Sydney hunts down a former nemesis and Adrian discovers a secret about spirit magic.

Fifteen-year-old Josh has chosen to side neither with his twin sister Sophie nor with the Alchemyst, Nicholas Flamel, but rather to fight alongside Dr. John Dee and the mysterious Virginia Dare, while the immortal Machiavelli and Billy the Kid follow the Elders' plans to set loose the monsters of Alcatraz on San Francisco and trigger the end of the humani race.

While armies of the Shadowrealms gather and Machiavelli goes to Alcatraz to kill Perenelle Flamel, fifteen-year-old twins Sophie and Josh Newman accompany the Alchemist to England to seek Gilgamesh.

During a crowded service at a cathedral in Germany, armed intruders in monks' robes unleash a nightmare of blood and destruction. But the killers have not come for gold; they seek a more valuable prize: the bones of the Magi who once paid homage to a newborn savior... a treasure that could reshape the world. With the Vatican in turmoil, SIGMA Force leaps into action. An elite team of scientific and Special Forces operatives under the command of Grayson...