When millions of fish start dying off the coast of Hawaii and something is destroying hundreds of ships, the government enlists the Flock--a band of genetically modified children who can fly--to help get to the bottom of the disaster before it is too late.

Since he was captured by the Glorious Path, a militant religion based on the teachings of a former soldier, fifteen-year-old Cal has served the Path in its brutal war with the remains of the United States government, and tried to survive and protect his younger brother, but when he kills an officer to protect a stray dog, Cal is forced take his brother and the dog and run.

Captain Meriwether Lewis's dog Seaman describes his experiences as he accompanies his master on the Lewis and Clark Expedition to explore the uncharted western wilderness.