Runaways Axi, sixteen, and Robinson, seventeen, who met on a cancer ward, leave small-town Oregon on a cross-country trip to experience the best of life before it is too late.

During her cross-country adventures following the tragic death of her family, Leila touches the lives of four strangers -- Hudson, Bree, Elliot, and Sonia. While forever changing the lives of these four, Leila also discovers an important truth about herself. A love-seeking mechanic, a dramatic petty thief, a disappointed planner, and a broken-hearted teen all find their lives transformed as each shares whirlwind adventures with a girl in an insanely...

Dan, Abby, and Jordan embark on a senior road trip to New Orleans, but as creepy occurrences escalate into near-death experiences, the trio realizes they will be lucky to make it out of this senior trip alive.

Courtney is about to embark on a cross-country road trip to college with her boyfriend, Jordan, when he dumps her. Despite the breakup, they decide to go on the trip together.

Sixteen-year-old Sophie has been frail and delicate since her premature birth, but discovers her true strength during a journey through Mexico, where the six-year-old orphan her family hopes to adopt was born, and to Guatemala, where her would-be boyfriend hopes to find his mother and plans to remain.