Ryan Sharma is a CHERUB agent. Working undercover, he can slip under adult radar and get information that sends criminals and terrorists to jail. Now he's investigating a double kidnapping, working with mission controller and old guard, James Adams. In the mission to end all missions, Ryan and James must assemble a team of legendary CHERUB agents to find the hostages and bring them home.

A new hero, a new mission: meet CHERUB's latest recruit. Twelve-year-old Ryan. Ryan's been waiting for a mission since he passed basic training eight months earlier. Ethan is his target. A privileged California boy, who likes computers and chess. He makes easy prey for school bullies, but his grandma runs a billion dollar crime syndicate in distant Kyrgyzstan. Ryan expects to enjoy the California lifestyle in a routine operation. But he's in for a...

James embarks on a dangerous mission for the CHERUB agency, taking down the world's most powerful drug lord, putting his own safety aside in the hopes of ridding the streets of dangerous drugs.

While undercover, Ryan, an agent for a secret organization of child spies who has saved Ethan's life multiple times, wonders if he can destroy Ethan's family-run criminal empire without hurting Ethan.