Beezus' biggest problem was her 4-year-old sister Ramona. Even though Beezus knew sisters were supposed to love each other, with a sister like Ramona, it seemed impossible.

Six-year-old Ramona Quimby must cope with a scary new bedroom, a job that steals away her mother's attention, and an unsympathetic first grade teacher.

Ramona at 7 1/2 sometimes feels discriminated against by being the youngest in the family.

Ramona's year in third grade is highlighted by the arrival of Howie's rich uncle, a change in her afterschool situation, a surprise wedding, a death and a new arrival in the family, and her father's getting a job.